Monday, 30 March 2009

Effect of Margin Status on Local Recurrence After Breast Conservation and Radiation Therapy for Ductal Carcinoma In Situ

Effect of Margin Status on Local Recurrence After Breast Conservation and Radiation Therapy for Ductal Carcinoma In Situ
Clive Dunne, John P. Burke, Monica Morrow, and Malcolm R. Kell
J Clin Oncol 27:1615-1620, 2009

Link to Journal

Surgical margins negative for DCIS should be obtained after BCS for DCIS. A margin threshold of 2 mm seems to be as good as a larger margin when BCS for DCIS is combined with RT

There is a difference between Europe and North America regards the amount of normal tissue that should be removed for clear margins in DCIS. In Europe, 10mm is the favoured margin, whereas 1mm may be regarded as clear in North America.

This study shows that a smaller margin combined with radiation therapy is as effective as taking a larger margin